Anti-MADD

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA038568.25 25 µl -

3 - 8 business days*

246.00€
ATA-HPA038568.100 100 µl -

3 - 8 business days*

491.00€
 
Protein function: Plays a significant role in regulating cell proliferation, survival and death... more
Product information "Anti-MADD"
Protein function: Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Isoform 5 shows increased cell proliferation and isoform 2 shows decreased. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms. Component of the TNFRSF1A signaling complex: MADD links TNFRSF1A with MAP kinase activation. Plays an important regulatory role in physiological cell death (TNF-alpha-induced, caspase-mediated apoptosis), isoform 1 is susceptible to inducing apoptosis, isoform 5 is resistant and isoform 3 and isoform 4 have no effect. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 98%
Keywords: Anti-Rab3 GDP/GTP exchange factor, Anti-Insulinoma glucagonoma clone 20, Anti-MAP kinase-activating death domain protein, Anti-Differentially expressed in normal and neoplastic cells
Supplier: Atlas Antibodies
Supplier-Nr: HPA038568

Properties

Application: IHC, ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: YSQQINEVLD QLANLNGRDL SIWSSGSRHM KKQTFVVHAG TDTNGDIFFM EVCDDCVVLR SNIGTVYERW WYEKLINMTY CPKTKVLCLW RRNGSETQ (ATA-APrEST80537)

Database Information

UniProt ID : Q8WXG6 | Matching products
Gene ID : GeneID 8567 | Matching products
Protein Atlas Nr. : ENSG00000110514

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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