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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R31695 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Mitotic spindle assembly checkpoint... more
Product information "Anti-Mad2L1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Mitotic spindle assembly checkpoint protein MAD2A is a protein that in humans is encoded by the MAD2L1 gene. This gene belongs to the MAD2 family. It is mapped to 4q27. MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The protein has two highly different native conformations, an inactive open conformation that cannot bind CDC20 and that predominates in cytosolic monomers, and an active closed conformation. It is required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment. Protein function: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore- spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. [The UniProt Consortium]
Keywords: | Anti-MAD2, Anti-HsMAD2, Anti-MAD2L1, Anti-MAD2-like protein 1, Anti-Mitotic arrest deficient 2-like protein 1, Anti-Mitotic spindle assembly checkpoint protein MAD2A, Mad2L1 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R31695 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Human partial recombinant protein (AA 2-205) was used as the immunogen for this Mad2L1 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K02537 | Matching products |
UniProt ID : | Q13257 | Matching products |
Gene ID | GeneID 4085 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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