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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ELK-ES4518.50 | 50 µl | - | - |
10 - 14 business days* |
173.00€
|
||
| ELK-ES4518.100 | 100 µl | - | - |
10 - 14 business days* |
290.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene is a member of the MAD gene family . The MAD genes encode basic... more
Product information "Anti-Mad 4"
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008], Protein function: Transcriptional repressor. Binds with MAX to form a sequence- specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. [The UniProt Consortium] Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Nucleus .
| Keywords: | Anti-MXD4, Anti-bHLHc12, Anti-BHLHC12, Anti-Max dimerizer 4, Anti-Max-associated protein 4, Anti-Max dimerization protein 4, Anti-Class C basic helix-loop-helix protein 12, Anti-Max-interacting transcriptional repressor MAD4, Mad 4 rabbit pAb |
| Supplier: | ELK Biotechnology |
| Supplier-Nr: | ES4518 |
Properties
| Application: | IHC, IF, ELISA |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MAD4. AA range:10-59 |
| Format: | Antiserum |
Database Information
| KEGG ID : | K09114 | Matching products |
| UniProt ID : | Q14582 | Matching products |
| Gene ID : | GeneID 10608 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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