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LYN is a tyrosine protein kinase that acts as an effector of EpoR (erythropoietin receptor) in... more
Product information "Anti-LYN"
LYN is a tyrosine protein kinase that acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation. LYN acts as the mediator that relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. It is involved in induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. LYN induces SAPK by a MKK7- and MEKK1-dependent mechanism. Alternate names for LYN include v-yes-1 Yamaguchi sarcoma viral related oncogene homolog, JTK8, and FLJ26625. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P07948]
| Keywords: | Anti-Tyrosine-protein kinase |
| Supplier: | Bethyl Laboratories |
| Supplier-Nr: | A302-683A |
Properties
| Application: | WB, IP |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Reactivity: | Human (Expected: Rat) |
| Immunogen: | synthetic peptide. The epitope recognized by A302-683A-T maps to a region between residue 1 and 50 of human v-yes-1 Yamaguchi sarcoma viral related oncogene homolog using the numbering given in entry NP_002341.1 (GeneID 4067). |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K05854 | Find alternatives |
| UniProt ID : | Q6NUK7 | Find alternatives |
| Gene ID | GeneID 4067 | Find alternatives |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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