Anti-Luteinizing Hormone alpha / hCG alpha, clone LHa/756

Anti-Luteinizing Hormone alpha / hCG alpha, clone LHa/756
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3277-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3277-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. This mAb reacts with... more
Product information "Anti-Luteinizing Hormone alpha / hCG alpha, clone LHa/756"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. This mAb reacts with a protein of ~13kDa, identified as alpha subunit of Luteinizing Hormone (LH) or Chorionic Gonadotrophin (CG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor, however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties. LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
Keywords: Anti-CGA, Anti-CG-alpha, Anti-LSH-alpha, Anti-FSH-alpha, Anti-TSH-alpha, Anti-Lutropin alpha chain, Anti-Thyrotropin alpha chain, Anti-Follitropin alpha chain, Anti-Choriogonadotropin alpha chain, Anti-Luteinizing hormone alpha chain, Luteinizing Hormone
Supplier: NSJ Bioreagents
Supplier-Nr: V3277-20UG

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: LHa/756
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant full-length human LHa protein was used as the immunogen for the Luteinizing Hormone alpha antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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