Anti-LTbetaR (mouse), clone 3C8 (preservative free)

Anti-LTbetaR (mouse), clone 3C8 (preservative free)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-20B-0041PF-C100 100 µg -

3 - 9 business days

308.00€
 
Monoclonal Antibody. Recognizes mouse LTbetaR. Isotype: Rat IgG1kappa. Clone: 3C8. Applications:... more
Product information "Anti-LTbetaR (mouse), clone 3C8 (preservative free)"
Monoclonal Antibody. Recognizes mouse LTbetaR. Isotype: Rat IgG1kappa. Clone: 3C8. Applications: FUNC (Blocking). Liquid. In PBS The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
Keywords: Anti-Lymphotoxin-beta Receptor, Anti-Tumor Necrosis Factor Receptor 2 Related Protein, Anti-Tumor Necrosis Factor C Receptor, Anti-Tumor Necrosis Factor Receptor Superfamily Member 3, Anti-TNFRSF3
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-20B-0041PF-C100

Properties

Application: FA (Blocking)
Antibody Type: Monoclonal
Clone: 3C8
Conjugate: No
Host: Rat
Reactivity: Mouse
Immunogen: Recombinant mouse LTbetaR (cysteine-rich region/aa 31-221).
Purity: >95% (SDS-PAGE)
Format: Liquid

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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