Anti-LTbetaR (mouse), clone 3C8 (preservative free)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
AG-20B-0041PF-C100	100 µg		-		3 - 9 business days*		319.00€

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Monoclonal Antibody. Recognizes mouse LTbetaR. Isotype: Rat IgG1kappa. Clone: 3C8. Applications:... more

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Product information "Anti-LTbetaR (mouse), clone 3C8 (preservative free)"

Monoclonal Antibody. Recognizes mouse LTbetaR. Isotype: Rat IgG1kappa. Clone: 3C8. Applications: FUNC (Blocking). Liquid. In PBS The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.

Keywords:	Anti-Lymphotoxin-beta Receptor, Anti-Tumor Necrosis Factor Receptor 2 Related Protein, Anti-Tumor Necrosis Factor C Receptor, Anti-Tumor Necrosis Factor Receptor Superfamily Member 3, Anti-TNFRSF3
Supplier:	AdipoGen Life Sciences
Supplier-Nr:	AG-20B-0041PF

Properties

Application:	FA (Blocking)
Antibody Type:	Monoclonal
Clone:	3C8
Conjugate:	No
Host:	Rat
Species reactivity:	mouse
Immunogen:	Recombinant mouse LTbetaR (cysteine-rich region/aa 31-221).
Purity:	>95% (SDS-PAGE)
Format:	Liquid