Anti-Lrwd1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
G-CAB21399.20	20 µl		-	-	9 - 20 business days*		103.00€
G-CAB21399.100	100 µl		-	-	9 - 20 business days*		398.00€

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Protein function: Required for G1/S transition. Recruits and stabilizes the origin recognition... more

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Product information "Anti-Lrwd1"

Protein function: Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post- replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability. [The UniProt Consortium]

Keywords:	Anti-ORCA, Anti-LRWD1, Anti-CENP-33, Anti-Centromere protein 33, Anti-ORC-associated protein, Anti-Origin recognition complex-associated protein, Anti-Leucine-rich repeat and WD repeat-containing protein 1, Lrwd1 Polyclonal Antibody
Supplier:	Assay Genie
Supplier-Nr:	CAB21399