Anti-LRWD1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA021320.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA021320.100	100 µl		-		7 - 10 business days*		491.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Required for G1/S transition. Recruits and stabilizes the origin recognition... more

Close menu

Product information "Anti-LRWD1"

Protein function: Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post- replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 76% and to rat: 77%

Keywords:	Anti-ORCA, Anti-LRWD1, Anti-CENP-33, Anti-Centromere protein 33, Anti-ORC-associated protein, Anti-Origin recognition complex-associated protein, Anti-Leucine-rich repeat and WD repeat-containing protein 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA021320

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PFLTVNDNLK VSFLLPTLRK VNGKDASSTY SQVENLNREL TSRVTAHWEK FMATLGPEEE AEKAQADFVK SAVRD (ATA-APrEST75050)