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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG42366.100 | 100 µg | - | - |
6 - 14 business days* |
658.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that... more
Product information "Anti-LRRC32 / GARP, clone GARP5"
Protein function: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3). [The UniProt Consortium]
| Keywords: | Anti-GARP, Anti-Garpin, Anti-D11S833E, Anti-Glycoprotein A repetitions predominant, Anti-Leucine-rich repeat-containing protein 32, Anti-Transforming growth factor beta activator LRRC32 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG42366 |
Properties
| Application: | WB |
| Antibody Type: | Monoclonal |
| Clone: | GARP5 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human |
| Immunogen: | Purified Human sGARP protein |
| MW: | 72 kD |
| Format: | Purified |
Database Information
| UniProt ID : | Q14392 | Matching products |
| Gene ID : | GeneID 2615 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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