Anti-LRRC32

Anti-LRRC32
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA055775.25 25 µl -

7 - 10 business days*

369.00€
ATA-HPA055775.100 100 µl -

7 - 10 business days*

491.00€
 
Protein function: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that... more
Product information "Anti-LRRC32"
Protein function: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 84% and to rat: 86%
Keywords: Anti-GARP, Anti-Garpin, Anti-D11S833E, Anti-Glycoprotein A repetitions predominant, Anti-Leucine-rich repeat-containing protein 32, Anti-Transforming growth factor beta activator LRRC32
Supplier: Atlas Antibodies
Supplier-Nr: HPA055775

Properties

Application: ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: NLDLSYNEIE LIPDSFLEHL TSLCFLNLSR NCLRTFEARR LGSLPCLMLL DLSHNALETL ELG (ATA-APrEST94168)

Database Information

UniProt ID : Q14392 | Matching products
Gene ID : GeneID 2615 | Matching products
Protein Atlas Nr. : ENSG00000137507

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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