Anti-LRPPRC

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-731A-T	10 µl (10 µg)		-		2 - 8 business days*		165.00€
A304-731A	100 µl (100 µg)		-		2 - 8 business days*		586.00€

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Protein function: May play a role in RNA metabolism in both nuclei and mitochondria. In the... more

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Product information "Anti-LRPPRC"

Protein function: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA. [The UniProt Consortium]

Keywords:	Anti-GP130, Anti-LRP130, Anti-LRPPRC, Anti-LRP 130, Anti-130 kDa leucine-rich protein, Anti-Leucine-rich PPR motif-containing protein, mitochondrial
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-731A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: chimpanzee, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A304-731A-T maps to a region between residue 1344 to 1394 of human Leucine-Rich Pentatricopeptide Repeat Containing using the numbering given in entry NP_573566.2 (GeneID 10128).
Format:	Antigen Affinity Purified