Anti-LRP1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA004182.25	25 µl		-		3 - 8 business days*		264.00€
ATA-HPA004182.100	100 µl		-		3 - 8 business days*		393.00€

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Protein function: Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic... more

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Product information "Anti-LRP1"

Protein function: Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells (PubMed:11907044, PubMed:12713657). Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2- macroglobulin receptor (PubMed:26142438, PubMed:1702392). Acts as TAU/MAPT receptor and controls the endocytosis of TAU/MAPT as well as its subsequent spread (PubMed:32296178). May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission (PubMed:12888553). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 93% and to rat: 93%

Keywords:	Anti-A2MR
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA004182

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: STCTVNQGNQ PQCRCLPGFL GDRCQYRQCS GYCENFGTCQ MAADGSRQCR CTAYFEGSRC EVNKCSRCLE GACVVNKQSG DVTCNCTDGR VAPSCLTCVG HCSNGGSCTM NSKMMPECQC PPHMTGPRCE EHVF (ATA-APrEST86741)