Anti-LIMD1

Anti-LIMD1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-182A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A303-182A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A303-182A 100 µl (20 µg) -

3 - 9 business days*

465.00€
 
Protein function: Adapter or scaffold protein which participates in the assembly of numerous... more
Product information "Anti-LIMD1"
Protein function: Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG- dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1- responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation. [The UniProt Consortium]
Keywords: Anti-LIMD1, Anti-LIM domain-containing protein 1
Supplier: Bethyl Laboratories
Supplier-Nr: A303-182A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Pig, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, European Domestic Ferret, Small-eared Galago, Thirteen-lined Ground Squirrel, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A303-182A-T maps to a region between residue 50 and 100 of human LIM Domains Containing 1 using the numbering given in entry NP_055055.1 (GeneID 8994).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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