Anti-LILRB2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-KC-2512.50	50 µl		-	-	Request delivery time estimate		206.00€
ABS-KC-2512.100	100 µl		-	-	Request delivery time estimate		295.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B,... more

Close menu

Product information "Anti-LILRB2"

Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:11169396, PubMed:12853576, PubMed:16455647, PubMed:20448110, PubMed:27859042). Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance (PubMed:20448110, PubMed:27859042, PubMed:16455647). Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions (PubMed:11875462, PubMed:12853576, PubMed:9548455, PubMed:9842885). [The UniProt Consortium]

Keywords:	Anti-Leukocyte immunoglobulin-like receptor subfamily B member 2, Anti-LIR-2, Anti-Leukocyte immunoglobulin-like receptor 2, Anti-CD85 antigen-like family member D, Anti-Immunoglobulin-like transcript 4, Anti-ILT-4, Anti-Monocyte/macrophage immunoglobulin
Supplier:	Absea
Supplier-Nr:	KC-2512