Anti-LGR5

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA012530.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA012530.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway... more

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Product information "Anti-LGR5"

Protein function: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 88% and to rat: 87%

Keywords:	Anti-LGR5, Anti-GPR49, Anti-G-protein coupled receptor 67, Anti-G-protein coupled receptor 49, Anti-G-protein coupled receptor HG38, Anti-Leucine-rich repeat-containing G-protein coupled receptor 5
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA012530

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AIIHPNAFST LPSLIKLDLS SNLLSSFPIT GLHGLTHLKL TGNHALQSLI SSENFPELKV IEMPYAYQCC AFGVCENAYK ISNQWNKGDN SSMDDLHKKD AGMFQAQDER DLEDFLLDFE EDLKALHSVQ CSPSPGPFKP CEHLLDG (ATA-APrEST71276)