Anti-LGALS3

Polyclonal Antibody against Human LGALS3, Gene description: galectin 3, Alternative Gene Names: GALIG, LGALS2, MAC-2, Validated applications: ICC, WB, Uniprot ID: P17931, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes. [The UniProt Consortium] Mouse gene identity: 89% Rat gene identity: 89%