Anti-LFNG

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA069130.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Glycosyltransferase that initiates the elongation of O-linked fucose residues... more

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Product information "Anti-LFNG"

Protein function: Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O- fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1 (PubMed:11346656). Essential mediator of somite segmentation and patterning. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 88% and to rat: 92%

Keywords:	Anti-LFNG, EC=2.4.1.222, Anti-Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe, Anti-O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA069130

Properties

Application:	WB, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TKKFHRARLD LLLETWISRH KEMTFIFTDG EDEALARHTG NVVITNCSAA H (ATA-APrEST88239)