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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA065246.25 | 25 µl | - |
7 - 10 business days* |
246.00€
|
|||
| ATA-HPA065246.100 | 100 µl | - |
7 - 10 business days* |
491.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Functions as a negative regulator of TGF-beta signaling and thereby probably... more
Product information "Anti-LDLRAD4"
Protein function: Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 81% and to rat: 81%
| Keywords: | Anti-LDLRAD4, Anti-C18orf1, Anti-Low-density lipoprotein receptor class A domain-containing protein 4 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA065246 |
Properties
| Application: | IHC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: HYKVSTRSFI NRPNQSRRRE DGLPQEGCLW PSDSAAPRLG ASEIMHAPRS RDRFTAPSFI QRDRFSRFQ (ATA-APrEST88129) |
Database Information
| UniProt ID : | O15165 | Matching products |
| Gene ID : | GeneID 753 | Matching products |
| Protein Atlas Nr. : | ENSG00000168675 |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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