Anti-LARGE1 (PE), clone LARGE-02

Anti-LARGE1 (PE), clone LARGE-02
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG42380.50 50 µg - -

6 - 14 business days*

551.00€
 
Protein function: Bifunctional glycosyltransferase with both xylosyltransferase and... more
Product information "Anti-LARGE1 (PE), clone LARGE-02"
Protein function: Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N- acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate- 6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:22223806). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4- xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide (PubMed:25279699). [The UniProt Consortium]
Keywords: Anti-KIAA0609, EC=2.4.-.-, Anti-Xylosyltransferase LARGE, Anti-Glycosyltransferase-like protein, Anti-Beta-1,3-glucuronyltransferase LARGE, Anti-Acetylglucosaminyltransferase-like 1A, Anti-LARGE xylosyl- and glucuronyltransferase 1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG42380

Properties

Application: FC
Antibody Type: Monoclonal
Clone: LARGE-02
Conjugate: Phycoerythrin
Host: Mouse
Species reactivity: human
Immunogen: Recombinant fragment corresponding to aa. 35-142 of Human LARGE1
MW: 88 kD
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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