Anti-LARGE

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R35864-100UG	100 µg		-	-	3 - 10 business days*		836.00€

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0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... more

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Product information "Anti-LARGE"

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Like-acetylglucosaminyltransferase Protein function: Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine- beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:22223806). Phosphorylated O- mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide (PubMed:25279699). [The UniProt Consortium]

Keywords:	Anti-LARGE, Anti-KIAA0609, EC=2.4.-.-, Anti-Xylosyltransferase LARGE, Anti-Beta-1,3-glucuronyltransferase LARGE, Anti-Acetylglucosaminyltransferase-like 1A, Anti-Glycosyltransferase-like protein LARGE1, LARGE Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	R35864

Properties

Application:	WB, ELISA (peptide)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human
Immunogen:	Amino acids SEADVNSENLQKQ were used as the immunogen for this LARGE antibody.
Format:	Purified