Anti-LARGE (aa421-433), Internal

Anti-LARGE (aa421-433), Internal
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG65221.100 100 µg - -

6 - 14 business days*

871.00€
 
Protein function: Bifunctional glycosyltransferase with both xylosyltransferase and... more
Product information "Anti-LARGE (aa421-433), Internal"
Protein function: Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine- beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:22223806). Phosphorylated O- mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide (PubMed:25279699). [The UniProt Consortium]
Keywords: Anti-LARGE, Anti-KIAA0609, EC=2.4.-.-, Anti-Xylosyltransferase LARGE, Anti-Beta-1,3-glucuronyltransferase LARGE, Anti-Acetylglucosaminyltransferase-like 1A, Anti-Glycosyltransferase-like protein LARGE1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG65221

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: human (Expected: canine, bovine)
Immunogen: C-SEADVNSENLQKQ
Format: Ammonium Sulfate Precipitated

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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