Anti-LAMP1/CD107a Monoclonal Recombinant Antibody
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| E-AN300057P.20 | 20 µl | - |
7 - 16 business days* |
182.00€
|
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| E-AN300057P.100 | 100 µl | - |
7 - 16 business days* |
462.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene is a member of a family of membrane glycoproteins. This... more
Product information "Anti-LAMP1/CD107a Monoclonal Recombinant Antibody"
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. Protein function: Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, lysosomal pH regulation, autophagy and cholesterol homeostasis (PubMed:37390818). Acts as an important regulator of lysosomal lumen pH regulation by acting as a direct inhibitor of the proton channel TMEM175, facilitating lysosomal acidification for optimal hydrolase activity (PubMed:37390818). Also plays an important role in NK-cells cytotoxicity (PubMed:2022921, PubMed:23632890). Mechanistically, participates in cytotoxic granule movement to the cell surface and perforin trafficking to the lytic granule (PubMed:23632890). In addition, protects NK-cells from degranulation-associated damage induced by their own cytotoxic granule content (PubMed:23847195). Presents carbohydrate ligands to selectins (PubMed:7685349). [The UniProt Consortium]
| Keywords: | LAMP-1, CD107a, CD107 antigen-like family member A, Lysosome-associated membrane protein 1, Lysosome-associated membrane glycoprotein 1, Recombinant LAMP1/CD107a Monoclonal Antibody |
| Supplier: | Elabscience |
| Supplier-Nr: | E-AN300057P |
Properties
| Application: | IHC (paraffin), FCM, ICC/IF, IP |
| Antibody Type: | Monoclonal |
| Clone: | 6G15 |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Human LAMP1 protein |
| Format: | Purified |
Database Information
| KEGG ID : | K06528 | Matching products |
| UniProt ID : | P11279 | Matching products |
| Gene ID : | GeneID 3916 | Matching products |
Handling & Safety
| Storage: | +4°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H317 |
| P Phrases: | P261, P272, P280, P302+352, P333+313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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