Anti-Lamin B Receptor

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG41789.100	100 µl		-	-	6 - 14 business days*		624.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of... more

Close menu

Product information "Anti-Lamin B Receptor"

Protein function: Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis (PubMed:9630650, PubMed:12618959, PubMed:16784888, PubMed:21327084, PubMed:27336722). Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation. Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation. Anchors the lamina and the heterochromatin to the inner nuclear membrane (PubMed:10828963). [The UniProt Consortium]

Keywords:	Anti-LBR, Anti-C14SR, Anti-LMN2R, Anti-Delta-14-SR, Anti-Lamin-B receptor, Anti-Sterol C14-reductase, Anti-C-14 sterol reductase, Anti-Delta(14)-sterol reductase LBR, Anti-3-beta-hydroxysterol Delta (14)-reductase
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41789

Properties

Application:	ICC, IF, IHC (paraffin), IP, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, rat
Immunogen:	Synthetic peptide of Human Lamin B Receptor
MW:	71 kD
Format:	Affinity Purified