Anti-L3MBTL1

Anti-L3MBTL1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA068051.25 25 µl -

7 - 10 business days*

335.00€
ATA-HPA068051.100 100 µl -

7 - 10 business days*

446.00€
 
Protein function: Polycomb group (PcG) protein that specifically recognizes and binds mono- and... more
Product information "Anti-L3MBTL1"
Protein function: Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post-translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/H1-4 at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at 'Lys-382', leading to repress p53/TP53- target genes. Also recognizes and binds RB1/RB monomethylated at 'Lys- 860'. Participates in the ETV6-mediated repression. Probably plays a role in cell proliferation. Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 33% and to rat: 31%
Keywords: Anti-L3MBTL1, Anti-KIAA0681, Anti-H-l(3)mbt, Anti-L(3)mbt-like, Anti-H-l(3)mbt protein, Anti-L(3)mbt protein homolog, Anti-Lethal(3)malignant brain tumor-like protein 1
Supplier: Atlas Antibodies
Supplier-Nr: HPA068051

Properties

Application: ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: STVAKWTIDE VFGFVQTLTG CEDQARLFKD EARIVRVTHV SGKTLVWTVA QLGDLVCSDH LQEGKGILET GVHSLLCSLP THLL (ATA-APrEST94300)

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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