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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
200-901-P11 | 100 µg | - | - |
6 - 10 business days* |
719.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-L1/ORF2 Antibody is directed against three regions within the endonuclease domain of L1 ORF2... more
Product information "Anti-L1/ORF2"
Anti-L1/ORF2 Antibody is directed against three regions within the endonuclease domain of L1 ORF2 protein. This product is an IgY fraction antibody purified from monospecific chicken egg yolks by a multi-step process which includes selective precipitation and salt fractionation followed by extensive dialysis against the buffer stated above. Reactivity occurs against mouse L1/ORF2 protein and is useful in determining its presence in various assays. A BLAST analysis shows reactivity with L1/ORF2 proteins from mouse sources based on 100% homology with the immunizing sequences. Cross reactivity against L1/ORF2 from other sources is unknown. Protein function: Has a reverse transcriptase activity required for target-primed reverse transcription of the LINE-1 element mRNA, a crucial step in LINE-1 retrotransposition. Has also an endonuclease activity that allows the introduction of nicks in the chromosomal target DNA. Cleaves DNA in AT-rich regions between a 5' stretch of purines and a 3' stretch of pyrimidines, corresponding to sites of LINE-1 integration in the genome. [The UniProt Consortium]
Keywords: | Anti-L1, Anti-Pol, Anti-ORF2p, Anti-Gm17492, EC=2.7.7.49, EC=3.1.21.-, Anti-Endonuclease, Anti-Reverse transcriptase, Anti-Long interspersed element-1, Anti-Retrovirus-related Pol polyprotein LINE-1, Anti-LINE-1 retrotransposable element ORF2 protein |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 200-901-P11 |
Properties
Application: | ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Chicken |
Species reactivity: | mouse |
Immunogen: | three synthetic peptides conjugated to keyhole limpet hemocyanin (KLH). The peptides correspond to regions within the endonuclease domain of L1/ORF2 protein. |
Format: | Purified |
Database Information
UniProt ID : | P11369 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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