Anti-KRT10 / Cytokeratin 10, clone KRT10/1948R

Anti-KRT10 / Cytokeratin 10, clone KRT10/1948R
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3632IHC-7ML 7 ml - -

3 - 10 business days*

752.00€
 
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only*.... more
Product information "Anti-KRT10 / Cytokeratin 10, clone KRT10/1948R"
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only*. This mAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Keywords: Anti-KPP, Anti-K10, Anti-CK-10, Anti-KRT10, Anti-Keratin-10, Anti-Cytokeratin-10, Anti-Keratin, type I cytoskeletal 10, KRT10 Antibody / Cytokeratin 10
Supplier: NSJ Bioreagents
Supplier-Nr: V3632IHC

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: KRT10/1948R
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: A cytoskeletal preparation extracted from human ectocervical epithelium was used as the immunogen for the recombinant CK10 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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