Anti-KMO

Anti-KMO
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA056942.25 25 µl -

7 - 10 business days*

246.00€
ATA-HPA056942.100 100 µl -

7 - 10 business days*

491.00€
 
Protein function: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form... more
Product information "Anti-KMO"
Protein function: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn) (PubMed:29429898, PubMed:23575632, PubMed:26752518, PubMed:28604669, PubMed:29208702). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 83% and to rat: 81%
Keywords: Anti-Kynurenine 3-hydroxylase, Anti-Kynurenine 3-monooxygenase
Supplier: Atlas Antibodies
Supplier-Nr: HPA056942

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: IALPNMNKSF TCTLFMPFEE FEKLLTSNDV VDFFQKYFPD AIPLIGEKLL VQDFFLLPAQ PMISVKCSSF HFKSHCVLLG DAAHAI (ATA-APrEST91767)

Database Information

KEGG ID : K00486 | Matching products
UniProt ID : O15229 | Matching products
Gene ID : GeneID 8564 | Matching products
Protein Atlas Nr. : ENSG00000117009

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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