Anti-KMO

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-J26	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-KMO was affinity purified from monospecific antiserum by immunoaffinity chromatography. This... more

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Product information "Anti-KMO"

Anti-KMO was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards Kynurenine 3-monooxygenase (KMO). A BLAST analysis was used to suggest cross-reactivity with Mouse based on 100% sequence homology. Cross-reactivity with KMO from other sources has not been determined. Protein function: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. [The UniProt Consortium]

Keywords:	Anti-KMO, EC=1.14.13.9, Anti-Kynurenine 3-hydroxylase, Anti-Kynurenine 3-monooxygenase
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-J26

Properties

Application:	ELISA, IHC, IFM, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse
Immunogen:	synthetic peptide corresponding to an internal region surrounding 200-300aa of the mouse KMO chain.
Format:	Purified