Anti-KLHL25

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG42145.50	50 µl		-	-	6 - 14 business days*		520.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex... more

Close menu

Product information "Anti-KLHL25"

Protein function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E. [The UniProt Consortium]

Keywords:	Anti-ENC2, Anti-ENC-2, Anti-KLHL25, Anti-Kelch-like protein 25, Anti-Ectoderm-neural cortex protein 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG42145

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat, cow, dog, guinea pig, swine, rabbit)
Immunogen:	Synthetic peptide around the N-terminal region of Human KLHL25. (within the following region: RLYEF SWRMC LVHFE TVRQS EDFNS LSKDT LLDLI SSDEL ETEDE RVVFE)
MW:	66 kD
Format:	Purified