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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA001165.25 | 25 µl | - |
7 - 10 business days* |
358.00€
|
|||
| ATA-HPA001165.100 | 100 µl | - |
7 - 10 business days* |
477.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Histone demethylase that specifically demethylates 'Lys-27' of histone H3,... more
Product information "Anti-KDM6A"
Protein function: Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code (PubMed:17851529, PubMed:17713478, PubMed:17761849). Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27' (PubMed:17851529, PubMed:17713478, PubMed:17761849). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (PubMed:17761849). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 97% and to rat: 97%
| Keywords: | Anti-UTX, Anti-KDM6A, Anti-Histone demethylase UTX, Anti-Lysine-specific demethylase 6A, Anti-[histone H3]-trimethyl-L-lysine(27) demethylase 6A, Anti-Ubiquitously-transcribed TPR protein on the X chromosome |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA001165 |
Properties
| Application: | IHC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SNSCILLDKC PPPRPPTSPY PPLPKDKLNP PTPSIYLENK RDAFFPPLHQ FCTNPKNPVT VIRGLAGALK LDLGLFSTKT LVEANNEHMV EVRTQLLQPA DENWDPTGTK KIWRCESNRS HTTI (ATA-APrEST74777) |
Database Information
| KEGG ID : | K11447 | Matching products |
| UniProt ID : | O15550 | Matching products |
| Gene ID : | GeneID 7403 | Matching products |
| Protein Atlas Nr. : | ENSG00000147050 |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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