Anti-KDM3A

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG40757.100 100 µl - -

6 - 14 business days*

624.00€
 
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3,... more
Product information "Anti-KDM3A"
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. Involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TNP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1. [The UniProt Consortium]
Keywords: Anti-KDM3A, Anti-JHDM2A, EC=1.14.11.-, Anti-Lysine-specific demethylase 3A, Anti-Jumonji domain-containing protein 1A, Anti-JmjC domain-containing histone demethylation protein 2A
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG40757

Properties

Application: IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthetic peptide within aa. 350-450 of Human KDM3A (NP_060903.2)
MW: 147 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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