Anti-KDM2A Recombinant

Anti-KDM2A Recombinant
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-RC-4920.50 50 µl - -

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206.00€
ABS-RC-4920.100 100 µl - -

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295.00€
 
Protein function: Histone demethylase that specifically demethylates 'Lys-36' of histone H3,... more
Product information "Anti-KDM2A Recombinant"
Protein function: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. Regulates circadian gene expression by repressing the transcriptional activator activity of CLOCK-ARNTL/BMAL1 heterodimer and RORA in a catalytically- independent manner (PubMed:26037310). [The UniProt Consortium]
Keywords: Anti-Lysine-specific demethylase 2A, Anti-CXXC-type zinc finger protein 8, Anti-F-box and leucine-rich repeat protein 11, Anti-F-box protein FBL7, Anti-F-box protein Lilina, Anti-F-box/LRR-repeat protein 11, Anti-JmjC domain-containing histone demethylati
Supplier: Absea
Supplier-Nr: RC-4920

Properties

Application: WB
Antibody Type: Monoclonal
Clone: 1R09
Conjugate: No
Host: Rabbit
Species reactivity: human
Format: Solution

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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