Anti-KCTD6

Anti-KCTD6
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-PACO38314.50 50 µg -

9 - 20 business days*

313.00€
 
KCTD6 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and... more
Product information "Anti-KCTD6"
KCTD6 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, IHC applications. KCTD6 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1, the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1, the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887). [The UniProt Consortium]
Keywords: Anti-KCTD6, Anti-KCASH3 protein, Anti-BTB/POZ domain-containing protein KCTD6, Anti-Potassium channel tetramerization domain-containing protein 6
Supplier: Assay Genie
Supplier-Nr: PACO38314

Properties

Application: ELISA, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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