Anti-KANK2, recombinant antibody

Anti-KANK2, recombinant antibody
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-RN-14782.50 50 µl - -

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232.00€
ABS-RN-14782.100 100 µl - -

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332.00€
 
Protein function: Involved in transcription regulation by sequestering in the cytoplasm nuclear... more
Product information "Anti-KANK2, recombinant antibody"
Protein function: Involved in transcription regulation by sequestering in the cytoplasm nuclear receptor coactivators such as NCOA1, NCOA2 and NCOA3 (PubMed:17476305). Involved in regulation of caspase-independent apoptosis by sequestering the proapoptotic factor AIFM1 in mitochondria (PubMed:22371500). Pro-apoptotic stimuli can induce its proteasomal degradation allowing the translocation of AIFM1 to the nucleus to induce apoptosis (PubMed:22371500). Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). Involved in actin stress fibers formation through its interaction with ARHGDIA and the regulation of the Rho signaling pathway (PubMed:17996375, PubMed:25961457). May thereby play a role in cell adhesion and migration, regulating for instance podocytes migration during development of the kidney (PubMed:25961457). Through the Rho signaling pathway may also regulate cell proliferation. [The UniProt Consortium]
Keywords: Anti-SIP, Anti-KANK2, Anti-ANKRD25, Anti-SRC-interacting protein, Anti-SRC1-interacting protein, Anti-SRC-1-interacting protein, Anti-Matrix-remodeling-associated protein 3, Anti-Ankyrin repeat domain-containing protein 25
Supplier: Absea
Supplier-Nr: RN-14782

Properties

Antibody Type: Monoclonal
Clone: K8U066_3C12
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: recombinant human KANK2
Format: Solution

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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