Anti-KANK1

Anti-KANK1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-882A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A301-882A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A301-882A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Involved in the control of cytoskeleton formation by regulating actin... more
Product information "Anti-KANK1"
Protein function: Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity, the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia, the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading, the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma. [The UniProt Consortium]
Keywords: Anti-KANK1, Anti-ANKRD15, Anti-Kidney ankyrin repeat-containing protein, Anti-Ankyrin repeat domain-containing protein 15, Anti-KN motif and ankyrin repeat domain-containing protein 1
Supplier: Bethyl Laboratories
Supplier-Nr: A301-882A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Mouse, Rat, Bovine, Horse, Pig, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Duckbill Platypus, Tasmanian Devil, White-tufted-ear Marmoset, Crab-eating Macaque, African Elephant, Chinese Hamster, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-882A-T maps to a region between residue 1302 and 1352 of human KN motif and ankyrin repeat domains 1 using the numbering given in entry NP_055973.2 (GeneID 23189).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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