Anti-JunD (Jun D proto-oncogene, AP-1, Transcription factor jun-D)

JunD is a member of the Jun family of nuclear transcription factors. It dimerizes with other Jun or , Fos family members to form the AP1 transcription factor. Unlike c-Jun or JunB, JunD antagonizes , Ras transformation and accumulates as cells enter quiescence. JunD is a 347aa, , 39kD protein (JunD-FL) that has a 303aa, 34kD isoform (delta JunD) which begins at aa44. Over the sequence used as an immunogen, human JunD shares 72% aa identity with mouse and rat JunD. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.