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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
J7998-10J.100 | 100 µg | - | - |
3 - 19 business days* |
675.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The JunB transcription factor, also known as JunB proto-oncogene, JunB oncogene, transcription... more
Product information "Anti-Jun B (JunB, Jun B proto-oncogene, Transcription factor jun-B)"
The JunB transcription factor, also known as JunB proto-oncogene, JunB oncogene, transcription factor JunB, and transforming protein JunB, is a basic region leucine zipper DNA-binding protein, and a member of the Jun family of proteins, which also includes c-Jun and JunD. Jun proteins can homodimerize or heterodimerize with other Jun family members, or heterodimerize with Fos family members (cFos, FosB, Fra-1, and Fra-2) to form the activator protein 1 (AP-1) transcription factor. The various dimers differ in their ability to transactivate AP-1-dependent genes. Jun B8 and JunD1 are almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. JunB and C-Jun antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin. Cyclin A is a direct transcriptional target of JunB driving cell proliferation. JunB is an important regulator of erythroid differentiation and is also important for the development of Th2 effector cells, normal Th2 cytokine expression pattern, and a complete Th2- dependent immune response in mice JunB expression levels are increased in human colorectal adenocarcinoma specimens as compared to normal mucosa. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000, Western Blot: 0.3-1ug/ml., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | J7998-10J |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human |
Immunogen: | Synthetic peptide corresponding to C-TLKAENAGLSSTAG, from the internal region of human Junb (NP_002220.1). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K09028 | Matching products |
UniProt ID : | P17275 | Matching products |
Gene ID | GeneID 3726 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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