Anti-JPT1

Item number	Size	Manual	Delivery time	Price
E-AB-52818.20	20 µl	-	7 - 16 business days*	89.00€
E-AB-52818.60	60 µl	-	7 - 16 business days*	174.00€
E-AB-52818.120	120 µl	-	7 - 16 business days*	292.00€
E-AB-52818.200	200 µl	-	7 - 16 business days*	485.00€

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Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces... more

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Product information "Anti-JPT1"

Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408). Protein function: Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408). [The UniProt Consortium]

Keywords:	Anti-ARM2, JPT1 Polyclonal Antibody
Supplier:	Elabscience
Supplier-Nr:	E-AB-52818

Properties

Application:	IHC, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Fusion protein of human JPT1

Database Information

UniProt ID :	Q9UK76 \| Matching products
Gene ID :	GeneID 51155 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	4°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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