Anti-JMY

Anti-JMY
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-573A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A302-573A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A302-573A 100 µl (20 µg) -

3 - 9 business days*

465.00€
 
Protein function: Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin... more
Product information "Anti-JMY"
Protein function: Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location. [The UniProt Consortium]
Keywords: Anti-JMY, Anti-Junction-mediating and -regulatory protein
Supplier: Bethyl Laboratories
Supplier-Nr: A302-573A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Gorilla, Chimpanzee, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A302-573A-T maps to a region between residue 800 and 850 of human junction mediating and regulatory protein using the numbering given in entry NP_689618.3 (GeneID 133746).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-JMY"
Write a review
or to review a product.
Viewed