Anti-JAM-A

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-891A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A302-891A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Seems to play a role in epithelial tight junction formation. Appears early in... more

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Product information "Anti-JAM-A"

Protein function: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6- PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha- L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840). [The UniProt Consortium]

Keywords:	Anti-JAM1, Anti-F11R, Anti-JAM-1, Anti-JAM-A, Anti-CD321, Anti-PAM-1, Anti-Platelet F11 receptor, Anti-Platelet adhesion molecule 1, Anti-Junctional adhesion molecule 1, Anti-Junctional adhesion molecule A
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-891A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat)
Immunogen:	synthetic peptide. The epitope recognized by A302-891A-T maps to a region between residue 249 and 299 of human Junctional Adhesion Molecule A using the numbering given in entry NP_058642.1 (GeneID 50848).
Format:	Antigen Affinity Purified