Anti-ITGB8

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA027797.25	25 µl		-		3 - 8 business days*		330.00€
ATA-HPA027797.100	100 µl		-		3 - 8 business days*		463.00€

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Protein function: Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin... more

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Product information "Anti-ITGB8"

Protein function: Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin (PubMed:1918072). It recognizes the sequence R-G-D in its ligands (PubMed:1918072). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs) (Probable). Required during vasculogenesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 85% and to rat: 85%

Keywords:	Anti-Integrin beta-8
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA027797

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AQHCVNSKGQ VCSGRGTCVC GRCECTDPRS IGRFCEHCPT CYTACKENWN CMQCLHPHNL SQAILDQCKT SCALMEQQHY (ATA-APrEST78062)