Anti-ITGB6 (Biotin)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-KB-3539.50	50 µl		-	-	Request delivery time estimate		206.00€
ABS-KB-3539.100	100 µl		-	-	Request delivery time estimate		295.00€

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Protein function: Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and... more

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Product information "Anti-ITGB6 (Biotin)"

Protein function: Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (PubMed:17545607, PubMed:17158881). It recognizes the sequence R-G-D in its ligands (PubMed:17545607, PubMed:17158881). Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion (PubMed:17545607, PubMed:17158881). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:17158881). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G- D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (PubMed:15184403, PubMed:22278742, PubMed:28117447). [The UniProt Consortium]

Keywords:	Anti-ITGB6, Anti-Integrin beta-6
Supplier:	Absea
Supplier-Nr:	KB-3539

Properties

Application:	ELISA
Antibody Type:	Monoclonal
Clone:	K52025_6D11
Conjugate:	Biotin
Host:	Mouse
Species reactivity:	human
Immunogen:	recombinant human ITGB6
Format:	Solution

Database Information

KEGG ID :	K06589 \| Matching products
UniProt ID :	P18564 \| Matching products
Gene ID :	GeneID 3694 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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