Anti-ITGB1 (Integrin beta-1, Fibronectin Receptor Subunit beta, VLA-4 Subunit beta, CD29, FNRB, MDF2

Integrin beta 1, also known as CD29, is a 130kD transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits 1 to 6 (CD49a to CD49f) also known as Very Late Antigens (VLA). CD29 is also called platelet GPIIa. The antigen mediates cellular adhesion and has broad cellular reactivity, but is not expressed by erythrocytes. In normal peripheral blood it is found on a subset of CD4+ and CD8+ T lymphocytes and on a minority of B lymphocytes. The "inducer" subpopulation of CD4+ lymphocytes co-express CD4 and CD29. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: A431 cells, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. , Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.