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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ABS-KC-3870.50 | 50 µl | - | - |
Request delivery time estimate |
206.00€
|
||
| ABS-KC-3870.100 | 100 µl | - | - |
Request delivery time estimate |
295.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of... more
Product information "Anti-ITGAM"
Protein function: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PubMed:9558116, PubMed:20008295). It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration (PubMed:28807980). In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (PubMed:21193407). May regulate phagocytosis-induced apoptosis in extravasated neutrophils. May play a role in mast cell development. Required with TYROBP/DAP12 in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development. [The UniProt Consortium]
| Keywords: | Anti-Integrin alpha-M, Anti-CD11 antigen-like family member B, Anti-CR-3 alpha chain, Anti-Cell surface glycoprotein MAC-1 subunit alpha, Anti-Leukocyte adhesion receptor MO1, Anti-Neutrophil adherence receptor, Anti-CD antigen CD11b, ITGAM Antibody |
| Supplier: | Absea |
| Supplier-Nr: | KC-3870 |
Properties
| Application: | IHC |
| Antibody Type: | Monoclonal |
| Clone: | 17G12 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human |
| Immunogen: | Recombinant human ITGAM |
| Format: | Solution |
Database Information
| KEGG ID : | K06461 | Matching products |
| UniProt ID : | P11215 | Matching products |
| Gene ID : | GeneID 3684 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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