Anti-ITGA5 Recombinant

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-RC-7044.50	50 µl		-	-	Request delivery time estimate		232.00€
ABS-RC-7044.100	100 µl		-	-	Request delivery time estimate		332.00€

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Protein function: Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and... more

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Product information "Anti-ITGA5 Recombinant"

Protein function: Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881). ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling (PubMed:29030430). ITGA5:ITGB3 is a receptor for soluble CD40LG and is required for CD40/CD40LG signaling (PubMed:31331973). [The UniProt Consortium]

Keywords:	Anti-Integrin alpha-5, Anti-CD49 antigen-like family member E, Anti-Fibronectin receptor subunit alpha, Anti-Integrin alpha-F, Anti-VLA-5, Anti-CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain, Anti-Integrin alpha-5 light chain], Recombinant
Supplier:	Absea
Supplier-Nr:	RC-7044

Properties

Antibody Type:	Monoclonal
Clone:	3M02
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Format:	Solution

Database Information

KEGG ID :	K06484 \| Matching products
UniProt ID :	P08648 \| Matching products
Gene ID :	GeneID 3678 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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