Anti-IRF9

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-KC-1389.50	50 µl		-	-	Request delivery time estimate		232.00€
ABS-KC-1389.100	100 µl		-	-	Request delivery time estimate		332.00€

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Protein function: Transcription factor that plays an essential role in anti- viral immunity. It... more

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Product information "Anti-IRF9"

Protein function: Transcription factor that plays an essential role in anti- viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. [The UniProt Consortium]

Keywords:	Anti-Interferon regulatory factor 9, Anti-IRF-9, Anti-IFN-alpha-responsive transcription factor subunit, Anti-ISGF3 p48 subunit, Anti-Interferon-stimulated gene factor 3 gamma, Anti-ISGF-3 gamma, Anti-Transcriptional regulator ISGF3 subunit gamma, IRF9 An
Supplier:	Absea
Supplier-Nr:	KC-1389

Properties

Antibody Type:	Monoclonal
Clone:	18H9
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant human IRF9
Format:	Solution

Database Information

KEGG ID :	K04693 \| Matching products
UniProt ID :	Q00978 \| Matching products
Gene ID :	GeneID 10379 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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