Anti-IRF5

Anti-IRF5
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA046700.25 25 µl -

7 - 10 business days*

330.00€
ATA-HPA046700.100 100 µl -

7 - 10 business days*

463.00€
 
Protein function: Transcription factor that plays a critical role in innate immunity by... more
Product information "Anti-IRF5"
Protein function: Transcription factor that plays a critical role in innate immunity by activating expression of type I interferon (IFN) IFNA and INFB and inflammatory cytokines downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9 (PubMed:11303025, PubMed:15695821, PubMed:22412986, PubMed:25326418, PubMed:32433612). Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN- stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction downstream of the TLR-activated, MyD88- dependent pathway. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 82% and to rat: 82%
Keywords: Anti-IRF-5, Anti-Interferon regulatory factor 5
Supplier: Atlas Antibodies
Supplier-Nr: HPA046700

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: NKSRDFRLIY DGPRDMPPQP YKIYEVCSNG PAPTDSQPPE DYSFGAGEEE E (ATA-APrEST81905)

Database Information

KEGG ID : K09446 | Matching products
UniProt ID : Q13568 | Matching products
Gene ID : GeneID 3663 | Matching products
Protein Atlas Nr. : ENSG00000128604

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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