Anti-IRF5

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-KC-1216.50	50 µl		-	-	Request delivery time estimate		232.00€
ABS-KC-1216.100	100 µl		-	-	Request delivery time estimate		332.00€

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Protein function: Transcription factor that plays a critical role in innate immunity by... more

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Product information "Anti-IRF5"

Protein function: Transcription factor that plays a critical role in innate immunity by activating expression of type I interferon (IFN) IFNA and INFB and inflammatory cytokines downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9 (PubMed:11303025, PubMed:15695821, PubMed:22412986, PubMed:25326418, PubMed:32433612). Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN- stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction downstream of the TLR-activated, MyD88- dependent pathway. [The UniProt Consortium]

Keywords:	Anti-Interferon regulatory factor 5, Anti-IRF-5, IRF5 Antibody
Supplier:	Absea
Supplier-Nr:	KC-1216

Properties

Antibody Type:	Monoclonal
Clone:	14B6
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant human IRF5
Format:	Solution

Database Information

KEGG ID :	K09446 \| Matching products
UniProt ID :	Q13568 \| Matching products
Gene ID :	GeneID 3663 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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