Anti-Interleukin-6 (IL-6) (bovine)

The Bovine IL-6 polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Bovine IL-6 ELISA. The Bovine IL-6 antibody was produced in chickens and is antigen-affinity purified. The reactivity by species is: (Bovine IL-6 - Strong) (Canine IL-6 - None) (Caprine IL-6 - Strong) (Chicken IL-6 - None) (Cynomolgus Monkey IL-6 - None) (Dolphin IL-6 - None) (Equine IL-6 - None) (Feline IL-6 - None) (Human IL-6 - None) (Mouse IL-6 - None) (Ovine IL-6 - Strong) (Rabbit IL-6 - None) (Swine IL-6 - None) (Zebrafish IL-6 - None). For research use only. Made in the USA Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane- bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells. [The UniProt Consortium]