Anti-INPP4B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA037681.25	25 µl		-		3 - 8 business days*		369.00€
ATA-HPA037681.100	100 µl		-		3 - 8 business days*		491.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol... more

Close menu

Product information "Anti-INPP4B"

Protein function: Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-trisphosphate (PubMed:24070612, PubMed:24591580). Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles (PubMed:24591580). The lipid phosphatase activity is critical for tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival (PubMed:19647222, PubMed:24070612). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 93%

Keywords:	Anti-INPP4B, Anti-Inositol polyphosphate 4-phosphatase type II, Anti-Type II inositol 3,4-bisphosphate 4-phosphatase
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA037681

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: ERRNTGYQFI YYSPENTAKA KEVLSNINQL QPLIATHADL LLNSASQHSP DSLKNSLKML SEKTELFVHA FKDQLVRSAL LALYTA (ATA-APrEST79709)